Drug allergy testing helps determine whether you truly have an immune-based allergy to medications such as penicillin or amoxicillin. Many people carry a penicillin allergy label based on a childhood reaction that may no longer be relevant or was never a true allergy. This service is especially helpful for patients who avoid penicillin due to past reactions, unclear history, or family concerns.

How It Works / What to Expect?

Testing begins with a careful review of your medical history, including details of any past reactions. Based on this information, the appropriate next steps are determined. Some patients require skin and intradermal testing, while others may safely proceed to a supervised medication challenge in the clinic. Testing is performed under close medical observation to ensure safety.

Types of Testing

• Skin testing and intradermal testing to evaluate immune response
• Medication challenge, when appropriate, to confirm tolerance
• Results are reviewed carefully and documented in your medical record

Based on the outcome, it is determined whether you are still allergic to penicillin.

Who Should Consider This Service?

Penicillin allergy testing may be recommended if:

• You were labeled allergic as a child, and the details are unclear
• Your reaction was mild or occurred many years ago
• You avoid penicillin due to a family member’s allergy
• Your doctor would prefer to prescribe penicillin, but you are listed as allergic
• You frequently need antibiotics and rely on second-line options

This testing is not performed during an active allergic reaction.