What It Is?

Hives are raised, itchy welts that can appear anywhere on the skin and may come and go quickly. Angioedema is similar but involves deeper swelling under the skin, especially around the eyes, lips, hands, or feet. Both conditions can be uncomfortable and unpredictable. Hives may last minutes to hours, while chronic hives persist for more than six weeks. Angioedema can cause pain or tightness, especially if swelling occurs near the airway.

Common Symptoms

• Red or skin-colored welts
• Itching or burning
• Welts that change shape or move around
• Swelling of the eyelids, lips, or face
• Warmth or tenderness in affected areas

Triggers and Causes

Acute triggers:

• Foods (nuts, shellfish, eggs, etc.)
• Medications like antibiotics or pain relievers
• Insect stings or bites
• Viral or bacterial infections
• Exercise or heat exposure

Chronic triggers (often autoimmune):

• Immune system activating allergy cells without an external allergen
• Thyroid disorders or other autoimmune conditions
• Stress, illness, or hormonal changes
• Pressure on the skin, such as tight clothing
• Temperature changes (hot showers, cold exposure)

When to See a Specialist?

You should see a specialist if hives are severe, recur frequently, or last longer than a few days. Swelling of the lips, tongue, or throat requires immediate medical attention. If over-the-counter antihistamines are not controlling your symptoms, or if symptoms disrupt sleep or work, an evaluation is necessary to determine underlying causes and better treatment options.