Immunoglobulin replacement therapy provides essential antibodies to people whose immune systems do not produce enough on their own. Antibodies (immunoglobulins) are proteins that help fight infections. When they are low or not working properly, even common illnesses can become frequent or severe. This therapy helps protect patients with confirmed immune deficiencies by supplying the antibodies their bodies are missing.

How It Works / What to Expect?

Immunoglobulin therapy replaces missing antibodies using purified immunoglobulins collected from carefully screened donors. Treatment does not cure the immune deficiency, but it significantly strengthens the body’s ability to fight infections.

Once an immune deficiency is diagnosed, treatment is tailored to maintain steady and protective antibody levels. Ongoing monitoring ensures the therapy remains safe and effective.

Types of Treatment

There are two main forms of immunoglobulin replacement therapy:

Intravenous Immunoglobulin (IVIG)

• Given through a vein
• Administered in the clinic or an infusion center
• Takes approximately 2 – 4 hours per session
• Typically given every 3-4 weeks
  

Subcutaneous Immunoglobulin (SCIG)

• Given under the skin
• Usually administered at home after training
• Takes approximately 1-2 hours per session
• Typically given once or twice weekly

The choice between IVIG and SCIG depends on medical needs, lifestyle, and personal preference.

Who Should Consider This Service?

Immunoglobulin replacement therapy is recommended only for patients with confirmed immune deficiencies. You may be a candidate if you have been diagnosed with:

• Primary immunodeficiency disorders, such as common variable immunodeficiency (CVID)
• Specific antibody deficiency with poor vaccine response
• Secondary hypogammaglobulinemia due to certain medical conditions or treatments

A full immune system evaluation is required before starting therapy.